Enzymatic hydrolysis of organophosphate insecticides, a possible pesticide disposal method

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Enzymatic hydrolysis of organophosphate insecticides, a possible pesticide disposal method.

A crude cell extract from a mixed bacterial culture growing on parathion, an organophosphate insecticide, hydrolyzed parathion (21 C) at a rate of 416 nmol/min per mg of protein. This rate of enzymatic hydrolysis, when compared with chemical hydrolysis by 0.1 N sodium hydroxide at 40 C, was 2, 450 times faster. Eight of 12 commonly used organophosphate insecticides were enzymatically hydrolyzed...

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Organophosphate compounds, which are potent irreversible inhibitors of carboxylic esterases, including cholinesterase, have been extensively used as pesticides throughout the world, and many unfortunate incidents of acute intoxication have been reported (Grob and Harvey, I953; Goldman and Teitel, I958; Healy, 1959; Dinman, I964; Quinby, I964; Crowley and Johns, I966; DePalma, Kwalick, and Zuker...

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 1976

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.32.1.7-13.1976